|
|
|
UNIT
NO |
NO
OF CREDITS |
TITLE
|
YEAR |
SEMESTER |
|
CPH-3010 |
4 |
Pharmacology
C
|
3 |
1 |
Learning Objectives
-
to understand the disposition of drugs in
the body and the effects of drug metabolising enzymes, and
organ clearance mechanisms in PK/PD
-
to understand the basic pharmacology and
mode of action of drugs used to treat neurological and
respiratory disorders; pharmacology of steroids
Content
-
Multi compartment models
-
Metabolism and biotransformation : Phase I
and phase II reactions
-
Physiological models in pharmacokinetics:
Hepatic and renal clearance
-
Pharmacokinetic principles in oral multiple
dosage drug regimens
-
Infusion drug regimens pharmacokinetics
-
Basic principles in epilepsy and
classification in epilepsy
-
Traditional antiepileptic drugs and new
antiepileptic drugs
-
Drugs used in other chronic neurological
and movement disorders;
-
Parkinson’s disease and Alzheimer’s disease
-
Drugs affecting the Nitric Oxide pathways
-
Inflammatory processes in asthma
-
Drugs used in asthma: beta2-adrenergic
receptor agonists, anticholinergic agents, methylxanthines,
antileukotrienes
-
Glucocorticoids: models of action at
cellular level, clincal effects, adeverse reactions, structure-activity relationships.
Type
Lectures, seminars, assignments, and credit test
Assessment
In the continuous and final mode: i.e.
continuous assessments and final credit test at end of study
unit.
Result
Percentage mark and grade
Lecturers
Prof. Roger Ellul-Micallef
Dr. Janet Mifsud
Dr. Anthony Fenech
Dr. Charles Scerri
Dr. Claude Farrugia
Dr. Maria Cordina |
