|
|
|
UNIT
NO |
NO
OF CREDITS |
TITLE
|
YEAR |
SEMESTER |
|
CPH-3011 |
4 |
Pharmacology D |
3 |
2 |
Learning Objectives
-
to
understand the basic pharmacology and mode of action of
drugs used in immunopharmacology, oncology and hormones
-
to present an overview of the molecular pharmacology of
specific drugs, and to discuss the molecular-based research
methodology and tools.
Content
-
Cell
differentiation and Antigen presenting cells
-
Immune
defence mechanisms: T cells and B cells
-
Cytokines
and Methods of immunosuppression
-
Basic
principles of chemotherapy and drugs used in oncology
-
Oral and
injectable hypoglycaemic agents
-
Thyroid hormones
-
Male and female sex hormones, contraceptives, HRT
-
Vitamin D and parathyroid hormone and Calcitonin
-
Recombinant drugs and Gene therapy
-
Bioinformatics, online databases, data mining
-
Specific receptor subtypes e.g. opioid receptors,
histamine receptors, insulin receptor, cytokine receptors
-
Molecular modes of action of enzyme modifiers e.g.
COX-inhibitors, cholinesterase inhibitors
-
Molecular aspects of discovery of novel drugs and
drug targets: The Human Genome database
-
Research tools for studying pharmacological actions
and pathways: overview of laboratory tools including PCR,
electrophoresis, sequencing, genotyping, molecular cloning, cell
culturing, transfections, expression analysis, microarray technology,
transgenic animals
Type
Lectures, seminars, assignments, and credit test
Assessment
In the continuous and final mode: i.e. continuous
assessments and final credit test at end of study unit
Result
Percentage mark and grade
Lecturers
Dr. Mark Micallef
Dr. Anthony Fenech
Dr. Janet Mifsud
Prof. F.F. Fenech |
