CPH-5112

Learning Objectives

To provide a sound understanding of the principles and techniques used in pharmacological analysis.

Content

Chemical analysis
Selection of biological fluid and time of sampling
 

Selection of analyate
  unchanged drug, metabolite, metabolic enzymes
 

Chromatographic techniques
  high performance liquid chromatography (HPLC)
  gas chromatography (GC)
 

Immunoassay techniques
  radio-immunoassay (RIA)
  enzyme-immunoassay (EIA)
  fluorescence-immunoassay (FIA)
 

Electrophoresis
  slab gel electrophoresis
  capillary electrophoresis
 

Automation in clinical drug analysis

Cell culture principles

Enzymatic analysis
  Enzyme activity measurements
 

Biological analysis

Bioassay

Assessment

Assignment (100%)

Lecturers

Dr. Janet Mifsud
Dr. Anna McElhatton